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Institution Date Title Author
國家衛生研究院 2025-01 Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design Tahiliani, H;Dhayalan, A;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2023-02-07 Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-02 What can the anti-apoptotic molecule, BIRC5/Survivin, do in the autophagic world? Cheung, CH;Lin, TY;Sarvagalla, S;Coumar, MS;Cheng, SM;Leung, E
國家衛生研究院 2021-04-16 Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors Reddy, JS;Chen, CM;Coumar, MS;Sun, HY;Sun, N;Hsieh, HP
國家衛生研究院 2021-02-22 Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design Chandar Charles, MR;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2020-08 The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells Chang, YC;Kondapuram, SK;Yang, TH;Syed, SB;Cheng, SM;Lin, TY;Lin, YC;Coumar, MS;Chang, JY;Leung, E;Cheung, CHA
國家衛生研究院 2020-07-07 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors Syed, SB;Lin, SY;Arya, H;Fu, IH;Yeh, TK;Charles, MRC;Periyasamy, L;Hsieh, HP;Coumar, MS
國家衛生研究院 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP
國家衛生研究院 2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Chandar Charles, MR;Mahesh, A;Lin, SY;Hsieh, HP;Dhayalan, A;Coumar, MS

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