| 臺大學術典藏 |
2021-07-06T07:01:19Z |
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth
|
Lai W.-T.;Cheng K.-L.;Baruchello R.;Rondanin R.;Marchetti P.;Simoni D.;Lee R.M.;Guh J.-H.;Lih-Ching Hsu; Lai W.-T.; Cheng K.-L.; Baruchello R.; Rondanin R.; Marchetti P.; Simoni D.; Lee R.M.; Guh J.-H.; LIH-CHING HSU |
| 臺大學術典藏 |
2021-07-06T07:01:19Z |
Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways
|
Leu W.-J.;Swain S.P.;Chan S.-H.;Hsu J.-L.;Liu S.-P.;Chan M.-L.;Yu C.-C.;Lih-Ching Hsu;Chou Y.-L.;Chang W.-L.;Hou D.-R.;Guh J.-H.; Leu W.-J.; Swain S.P.; Chan S.-H.; Hsu J.-L.; Liu S.-P.; Chan M.-L.; Yu C.-C.; LIH-CHING HSU; Chou Y.-L.; Chang W.-L.; Hou D.-R.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:18Z |
Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways
|
Chan M.-L.; Yu C.-C.; Hsu J.-L.; Leu W.-J.; Chan S.-H.; LIH-CHING HSU; Liu S.-P.; Ivantcova P.M.; Dogan ?.; Br?se S.; Kudryavtsev K.V.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:16Z |
The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cells
|
Li Y.-L.;Weng H.-C.;Hsu J.-L.;Lin S.-W.;Guh J.-H.;Lih-Ching Hsu; Li Y.-L.; Weng H.-C.; Hsu J.-L.; Lin S.-W.; Guh J.-H.; LIH-CHING HSU |
| 臺大學術典藏 |
2021-07-06T07:01:16Z |
Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systems
|
Chang J.-F.;Hsu J.-L.;Sheng Y.-H.;Leu W.-J.;Yu C.-C.;Chan S.-H.;Chan M.-L.;Lih-Ching Hsu;Liu S.-P.;Guh J.-H.; Chang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; LIH-CHING HSU; Liu S.-P.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:16Z |
Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contents
|
Hsu J.-L.; Leu W.-J.; LIH-CHING HSU; Liu S.-P.; Zhong N.-S.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:15Z |
Discovery of novel agents on spindle assembly checkpoint to sensitize vinorelbine-induced mitotic cell death against human non-small cell lung cancers
|
Chang Y.-C.; Tseng Y.-L.; Leu W.-J.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU; Hsu J.-L.; Hou D.-R.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:15Z |
Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity
|
Marchesi E.;Chinaglia N.;Capobianco M.L.;Marchetti P.;Huang T.-E.;Weng H.-C.;Guh J.-H.;Lih-Ching Hsu;Perrone D.;Navacchia M.L.; Marchesi E.; Chinaglia N.; Capobianco M.L.; Marchetti P.; Huang T.-E.; Weng H.-C.; Guh J.-H.; LIH-CHING HSU; Perrone D.; Navacchia M.L. |
| 臺大學術典藏 |
2021-07-06T07:01:14Z |
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
|
Hsu J.-L.; Leu W.-J.; LIH-CHING HSU; Ho C.-H.; Liu S.-P.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:14Z |
The (+)-brevipolide H displays anticancer activity against human castration-resistant prostate cancer: The role of oxidative stress and Akt/mTOR/p70S6K dependent pathways in G1 checkpoint arrest and apoptosis
|
Sheng Y.-H.; Leu W.-J.; Chen C.-N.; Hsu J.-L.; Liu Y.-T.; LIH-CHING HSU; Hou D.-R.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:13Z |
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies
|
Leu W.-J.; Chu J.-C.; Hsu J.-L.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU; Huang W.-J.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-06T07:01:13Z |
Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
|
Huang T.-E.; Deng Y.-N.; Hsu J.-L.; Leu W.-J.; Marchesi E.; Capobianco M.L.; Marchetti P.; Navacchia M.L.; Guh J.-H.; Perrone D.; LIH-CHING HSU |
| 臺大學術典藏 |
2021-07-05T07:59:50Z |
Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells
|
Huang D.-M.; Shen Y.-C.; Wu C.; Huang Y.-T.; FAN-LU KUNG; Teng C.-M.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:49Z |
Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells
|
Chiang P.-C.; FAN-LU KUNG; Huang D.-M.; Li T.-K.; Fan J.-R.; Pan S.-L.; Shen Y.-C.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:48Z |
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway
|
Lu P.-H.; Chueh S.-C.; FAN-LU KUNG; Pan S.-L.; Shen Y.-C.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:48Z |
Investigation of anti-tumor mechanisms of K2154: Characterization of tubulin isotypes, mitotic arrest and apoptotic machinery
|
Lu P.-H.; FAN-LU KUNG; Kuo S.-C.; Chueh S.-C.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:47Z |
Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancer
|
Hsu J.-L.; Pan S.-L.; Ho Y.-F.; Hwang T.-L.; FAN-LU KUNG; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:47Z |
Cryptocaryone, a Natural Dihydrochalcone, Induces Apoptosis in Human Androgen Independent Prostate Cancer Cells by Death Receptor Clustering in Lipid Raft and Nonraft Compartments
|
Chen Y.-C.; FAN-LU KUNG; Tsai I.-L.; Chou T.-H.; Chen I.-S.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:46Z |
Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancer
|
Lu P.-H.; Yu C.-C.; Chiang P.-C.; Chen Y.-C.; Ho Y.-F.; FAN-LU KUNG; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:45Z |
Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation
|
Liu F.-L.; Hsu J.-L.; Lee Y.-J.; Dong Y.-S.; FAN-LU KUNG; Chen C.-S.; Guh J.-H. |
| 臺大學術典藏 |
2021-07-05T07:59:45Z |
Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma
|
Hsu J.-L.; Liu F.-L.; Hsu L.-C.; Chang H.-S.; Leu W.-J.; Yu C.-C.; Chang W.-L.; Chen I.-S.; FAN-LU KUNG; Guh J.-H. |
| 臺大學術典藏 |
2021-06-04T08:33:29Z |
Combined treatment with denbinobin and fas ligand has a synergistic cytotoxic effect in human pancreatic adenocarcinoma Bxpc-3 Cells
|
CHIA-RON YANG; Guh J.H.; Teng C.M.; Chen C.C.; Chen P.H. |
| 臺大學術典藏 |
2021-06-04T06:23:34Z |
Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways
|
Chiang P.-C.; Lin S.-C.; Pan S.-L.; CHING-HUA KUO; Tsai I.-L.; Kuo M.-T.; Wen W.-C.; Chen P.; Guh J.-H. |
| 臺大學術典藏 |
2021-06-04T03:09:24Z |
Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
|
Yeh T.-C.; Chiang P.-C.; Li T.-K.; Hsu J.-L.; CHUN-JUNG LIN; Wang S.-W.; Peng C.-Y.; Guh J.-H. |
| 臺大學術典藏 |
2021-05-07T05:13:34Z |
Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors
|
Huang W.-J.; CHING-CHOW CHEN; Chao S.-W.; Yu C.-C.; Yang C.-Y.; Guh J.-H.; Lin Y.-C.; Kuo C.-I.; Yang P.; Chang C.-I. |
| 臺大學術典藏 |
2021-04-15T07:52:55Z |
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma
|
Chiang P.-C.; Chien C.-L.; Pan S.-L.; WEN-PIN CHEN; Teng C.-M.; Shen Y.-C.; Guh J.-H. |
| 臺大學術典藏 |
2021-02-02T00:43:15Z |
Anti-angiogenic effects and mechanism of prazosin
|
Liao C.-H.; Guh J.-H.; Chueh S.-C.; HONG-JENG YU |
| 臺大學術典藏 |
2021-02-02T00:43:06Z |
Erratum: Anti-angiogenic effects and mechanism of prazosin (The Prostate (2011) 71 (976-984))
|
Liao C.-H.; Guh J.-H.; Chueh S.-C.; HONG-JENG YU |
| 臺大學術典藏 |
2021-01-29T03:17:24Z |
A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway
|
Hsu J.-L.;Shih-Ping Liu;Lee C.-C.;Hsu L.-C.;Ho Y.-F.;Huang H.-S.;Guh J.-H.; Hsu J.-L.; SHIH-PING LIU; Lee C.-C.; Hsu L.-C.; Ho Y.-F.; Huang H.-S.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:21Z |
A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i
|
Yu C.-C.;Pan S.-L.;Chao S.-W.;Shih-Ping Liu;Hsu J.-L.;Yang Y.-C.;Li T.-K.;Huang W.-J.;Guh J.-H.; Yu C.-C.; Pan S.-L.; Chao S.-W.; SHIH-PING LIU; Hsu J.-L.; Yang Y.-C.; Li T.-K.; Huang W.-J.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:19Z |
KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora a activity
|
Yu C.-C.;Shih-Ping Liu;Hsu J.-L.;Hsu J.T.A.;Kudryavtsev K.;Guh J.-H.; Yu C.-C.; SHIH-PING LIU; Hsu J.-L.; Hsu J.T.A.; Kudryavtsev K.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:19Z |
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway
|
Ho C.-H.;Hsu J.-L.;Shih-Ping Liu;Hsu L.-C.;Chang W.-L.;Chao C.C.-K.;Guh J.-H.; Ho C.-H.; Hsu J.-L.; SHIH-PING LIU; Hsu L.-C.; Chang W.-L.; Chao C.C.-K.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:17Z |
Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways
|
Leu W.-J.; Swain S.P.; Chan S.-H.; Hsu J.-L.; SHIH-PING LIU; Chan M.-L.; Yu C.-C.; Hsu L.-C.; Chou Y.-L.; Chang W.-L.; Hou D.-R.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:15Z |
Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways
|
Chan M.-L.;Yu C.-C.;Hsu J.-L.;Leu W.-J.;Chan S.-H.;Hsu L.-C.;Shih-Ping Liu;Ivantcova P.M.;Dogan ?.;Br?Se S.;Kudryavtsev K.V.;Guh J.-H.; Chan M.-L.; Yu C.-C.; Hsu J.-L.; Leu W.-J.; Chan S.-H.; Hsu L.-C.; SHIH-PING LIU; Ivantcova P.M.; Dogan ?.; Br?se S.; Kudryavtsev K.V.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:14Z |
Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contents
|
Hsu J.-L.;Leu W.-J.;Hsu L.-C.;Shih-Ping Liu;Zhong N.-S.;Guh J.-H.; Hsu J.-L.; Leu W.-J.; Hsu L.-C.; SHIH-PING LIU; Zhong N.-S.; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:13Z |
Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systems
|
Chang J.-F.;Hsu J.-L.;Sheng Y.-H.;Leu W.-J.;Yu C.-C.;Chan S.-H.;Chan M.-L.;Hsu L.-C.;Shih-Ping Liu;Guh J.-H.; Chang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; Hsu L.-C.; SHIH-PING LIU; Guh J.-H. |
| 臺大學術典藏 |
2021-01-29T03:17:11Z |
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
|
Hsu J.-L.; Leu W.-J.; Hsu L.-C.; Ho C.-H.; SHIH-PING LIU; Guh J.-H. |
| 臺大學術典藏 |
2020-12-28T05:56:09Z |
A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways
|
Guh J.-H.; Bastow K.F.; Lee K.-H.; Nakagawa-Goto K.; Yu C.-C.; Chiang P.-C.; TING-CHUN KUO |
| 臺大學術典藏 |
2020-12-28T05:56:09Z |
WJ9708012 exerts anticancer activity through PKC-α related crosstalk of mitochondrial and endoplasmic reticulum stresses in human hormone-refractory prostate cancer cells
|
TING-CHUN KUO; Huang W.-J.; Guh J.-H. |
| 臺大學術典藏 |
2020-06-22T07:36:56Z |
The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cells
|
Li Y.-L.;Weng H.-C.;Hsu J.-L.;Shu-Wha Lin;Guh J.-H.;Hsu L.-C.; Li Y.-L.; Weng H.-C.; Hsu J.-L.; SHU-WHA LIN; Guh J.-H.; Hsu L.-C. |
| 臺大學術典藏 |
2020-02-27T01:50:16Z |
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma
|
Chiang P.-C.;Chung-Liang Chien;Pan S.-L.;Chen W.-P.;Teng C.-M.;Shen Y.-C.;Guh J.-H.; Chiang P.-C.; CHUNG-LIANG CHIEN; Pan S.-L.; Chen W.-P.; Teng C.-M.; Shen Y.-C.; Guh J.-H. |
| 臺大學術典藏 |
2020-02-06T10:53:30Z |
Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology
|
Huang H.-S.; JING-JER LIN; Guh J.-H.; Huang K.-F.; Huang F.-C.; Hsieh H.-H.; Lee C.-C.; Chen T.-C.; Chang D.-M.; Chen C.-L.; Chen C.-L.;Chang D.-M.;Chen T.-C.;Lee C.-C.;Hsieh H.-H.;Huang F.-C.;Huang K.-F.;Guh J.-H.;Jing-Jer Lin;Huang H.-S. |
| 臺大學術典藏 |
2020-02-06T10:53:26Z |
Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents
|
Chen T.-C.;Guh J.-H.;Hsu H.-W.;Chen C.-L.;Lee C.-C.;Wu C.-L.;Lee Y.-R.;Jing-Jer Lin;Yu D.-S.;Huang H.-S.; Chen T.-C.; Guh J.-H.; Hsu H.-W.; Chen C.-L.; Lee C.-C.; Wu C.-L.; Lee Y.-R.; JING-JER LIN; Yu D.-S.; Huang H.-S. |
| 臺大學術典藏 |
2019 |
Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents
|
Chen T.-C.;Yu D.-S.;Chen S.-J.;Chen C.-L.;Lee C.-C.;Hsieh Y.-Y.;Chang L.-C.;Guh J.-H.;Jing-Jer Lin;Huang H.-S.; Huang H.-S.; JING-JER LIN; Guh J.-H.; Chang L.-C.; Hsieh Y.-Y.; Chen T.-C.; Yu D.-S.; Chen S.-J.; Chen C.-L.; Lee C.-C. |
| 臺大學術典藏 |
2018-09-10T15:27:37Z |
Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents
|
Chen, T.-C.;Yu, D.-S.;Chen, S.-J.;Chen, C.-L.;Lee, C.-C.;Hsieh, Y.-Y.;Chang, L.-C.;Guh, J.-H.;Lin, J.-J.;Huang, H.-S.; JIH-HWA GUH; JING-JER LIN |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers
|
Kudryavtsev, K.V.;Ivantcova, P.M.;Muhle-Goll, C.;Churakov, A.V.;Sokolov, M.N.;Dyuba, A.V.;Arutyunyan, A.M.;Howard, J.A.K.;Yu, C.-C.;Guh, J.-H.;Zefirov, N.S.;Br\\Ase, S.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation
|
Chang, W.-L.;Hsu, L.-C.;Leu, W.-J.;Chen, C.-S.;Guh, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents
|
Lee, Y.-R.;Chen, T.-C.;Lee, C.-C.;Chen, C.-L.;Ahmed Ali, A.A.;Tikhomirov, A.;Guh, J.-H.;Yu, D.-S.;Huang, H.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Structural studies and anticancer activity of a novel class of β-peptides
|
Kudryavtsev, K.V.;Yu, C.-C.;Ivantcova, P.M.;Polshakov, V.I.;Churakov, A.V.;Br\\Ase, S.;Zefirov, N.S.;Guh, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry
|
Chang, W.-L.;Yu, C.-C.;Chen, C.-S.;Guh, J.-H.; JIH-HWA GUH |
