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Institution Date Title Author
亞洲大學 2004 Discovery and Analysis of Tumor-specific Alternative Splicing Sites Chen Chia Yang
臺大學術典藏 2022-02-21T23:31:30Z Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formation Chou, Chun Chi; KUO-TAI HUA; Chen, Min Wei; Wu, Chin Jui; CHUN-HUA HSU; JANN-TAY WANG; Hsiao, Michael; Wei, Lin Hung
臺大學術典藏 2022-05-13T08:04:01Z Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formation Chou C.-C.; Hua K.-T.; Chen M.-W.; Wu C.-J.; Hsu C.-H.; JANN-TAY WANG; Hsiao M.; Wei L.-H.
臺大學術典藏 2022-06-17T02:55:22Z Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formation Chou, Chun-Chi; Hua, Kuo-Tai; Chen, Min-Wei; Wu, Chin-Jui; Hsu, Chun-Hua; Wang, Jann-Tay; Hsiao, Michael; Wei, Linlin
臺大學術典藏 2022-06-17T03:31:49Z Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formation Chou, Chun-Chi; Hua, Kuo-Tai; Chen, Min-Wei; Wu, Chin-Jui; Hsu, Chun-Hua; Wang, Jann-Tay; Hsiao, Michael; LING-HUNG WEI
國立成功大學 2023 Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis Ahmadi, Ahmadi A.R.;Song, G.;Gao, T.;Ma, J.;Han, X.;Hu, M.-W.;Cameron, A.M.;Wesson, R.N.;Philosophe, B.;Ottmann, S.;King, E.;Gurakar, A.;Qi, L.;Peiffer, B.;Burdick, J.;Anders, R.;Zhou, Zhou Z.;Lu, H.;Feng, D.;Chen, Chen C.-S.;Qian, J.;Gao, B.;Zhu, H.;Sun, Z.
臺大學術典藏 2021-07-26T09:44:09Z Discovery and characterization of diterpene synthases in Chamaecyparis formosensis Matsum. which participated in an unprecedented diterpenoid biosynthesis route in conifer Ma L.-T;Wang C.-H;Hon C.-Y;Lee Y.-R;Chu F.-H.; Ma L.-T; Wang C.-H; Hon C.-Y; Lee Y.-R; Chu F.-H.; FANG-HUA CHU
臺大學術典藏 2021-01-19T12:08:17Z Discovery and characterization of diterpene synthases in Chamaecyparis formosensis Matsum. which participated in an unprecedented diterpenoid biosynthesis route in conifer Ma, Li Ting; Wang, Chang Hsin; Hon, Chong Yao; Lee, Yi Ru; FANG-HUA CHU
中國醫藥大學 2005-12-12 Discovery and characterization of novel transcription binding motifs in the promoters of primate eosinophil RNases. 張顥騰(Hao-Teng Chang); (Chang, Y.-H.,); (Pai, T.-W.,); (Fan, T.-c.,); (Chou, W.I.); (Chang, M. D.-T.)*
中國醫藥大學 2006-02-13 Discovery and characterization of novel transcription binding motifs in the promoters of primate eosinophil RNases. 張顥騰(Hao-Teng Chang); (Chang, Y.-H.,); (Pai, T.-W.,); (Fan, Tc); (Chou, W.-I,); (Chang, M. D.-T.)*
國家衛生研究院 2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design Yeh, TK;Song, JS;Chang, PW;Yu, JC;Chang, CH;Liao, FY;Tien, YW;Kuppusamy, R;Li, AS;Chen, CH;Chen, CW;Lin, LM;Chang, HH;Huang, CH;Yao, JY;Wu, MH;Peng, YH;Hsueh, CC;Hsiao, WC;Chen, PH;Lin, CY;Hsieh, SH;Shih, C;Hung, MS;Wu, SY;Kuo, CC;Ueng, SH
國立成功大學 2022 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design Yeh, T.-K.;Song, J.-S.;Chang, P.-W.;Yu, J.-C.;Chang, Chang C.-H.;Liao, F.-Y.;Tien, Y.-W.;Kuppusamy, R.;Li, A.-S.;Chen, Chen C.-H.;Chen, Chen C.-W.;Lin, Lin L.-M.;Chang, H.-H.;Huang, C.-H.;Yao, J.-Y.;Wu, M.-H.;Peng, Y.-H.;Hsueh, C.-C.;Hsiao, W.-C.;Chen, P.-H.;Lin, C.-Y.;Hsieh, S.-H.;Shih, C.;Hung, M.-S.;Wu, S.-Y.;Kuo, C.-C.;Ueng, S.-H.
國家衛生研究院 2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer Hsieh, HP;Hsu, JTA;Yeh, TK;Chen, CT
國家衛生研究院 2009-03 Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
嘉南藥理大學 2011 Discovery and Development of Novel VEGFR3 Inhibitors as the Targeted Cancer Therapies Li-Hsun Chen (陳立勳); Chih-HauChen (陳志豪); Wei-Jiunn Lee (李維駿); Min-Liang Kuo (郭明良); Chung-Ming Sun (孫仲銘)
中臺科技大學 2011-03-23 Discovery and Development of Plant-Derived Agents for Translational Research 吳永昌
國家衛生研究院 2016-04 Discovery and development of tylophorine derived dibenzoquinolines-33b compounds into therapeutic agents Lee, SJ;Li, CH;Lee, YZ;Yang, CW
嘉南藥理大學 2019 Discovery and Elucidation of the Biosynthesis of Aspernidgulenes: Novel Polyenes from Aspergillus Nidulans by Using Serial Promoter Replacement Lin, Tzu-Shyang; Chen, Bethany; Chiang, Yi-Ming; Wang, Clay C. C.
國立臺灣大學 1987 Discovery and Epidemiology of PCB Poisoning in Taiwan:a Four Year Followup 許須美; Ma, C. I.; Hsu, Steve K. H.; Wu, S. S.; Hsu, Nora H. M.; 葉金川; Wu, S. B.; Hsu, Hsu-Mei; Ma, C. I.; Hsu, Steve K. H.; Wu, S. S.; Hsu, Nora H. M.; Yeh, Chin-Chuan; Wu, S. B.
國家衛生研究院 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT
臺大學術典藏 2020-05-04T08:09:16Z Discovery and fusion of salient multimodal features toward news story segmentation. Hsu, Winston H.; Chang, Shih-Fu; Huang, Chih-Wei; Kennedy, Lyndon S.; Lin, Ching-Yung; Iyengar, Giridharan; WINSTON HSU
中國醫藥大學 2004-02-08 Discovery and identification of polar glycolipids with immunomodulator activities isolated from indigenous thermophilic bacteria Thermus and Meiotherm 陸自利(Lu,Tsu-Li)
國家衛生研究院 2013-11 Discovery and refinement of loci associated with lipid levels WWiller, CJ;Schmidt, EM;Sengupta, S;Peloso, GM;Gustafsson, S;Kanoni, S;Ganna, A;Chen, J;Buchkovich, ML;Mora, S;Beckmann, JS;Bragg-Gresham, JL;Chang, HY;Demirkan, A;Den Hertog, HM;Do, R;Donnelly, LA;Ehret, GB;Esko, T;Feitosa, MF;Ferreira, T;Fischer, K;Fontanillas, P;Fraser, RM;Freitag, DF;Gurdasani, D;Heikkilä, K;Hyppönen, E;Isaacs, A;Jackson, AU;Johansson, Å;Johnson, T;Kaakinen, M;Kettunen, J;Kleber, ME;Li, X;Luan, J;Lyytikäinen, LP;Magnusson, PKE;Mangino, M;Mihailov, E;Montasser, ME;Müller-Nurasyid, M;Nolte, IM;O'Connell, JR;Palmer, CD;Perola, M;Petersen, AK;Sanna, S;Saxena, R;Service, SK;Shah, S;Shungin, D;Sidore, C;Song, C;Strawbridge, RJ;Surakka, I;Tanaka, T;Teslovich, TM;Thorleifsson, G;Van Den Herik, EG;Voight, BF;Volcik, KA;Waite, LL;Wong, A;Wu, Y;Zhang, W;Absher, D;Asiki, G;Barroso, I;Been, LF;Bolton, JL;Bonnycastle, LL;Brambilla, P;Burnett, MS;Cesana, G;Dimitriou, M;Doney, ASF;Döring, A;Elliott, P;Epstein, SE;Eyjolfsson, GI;Gigante, B;Goodarzi, MO;Grallert, H;Gravito, ML;Groves, CJ;Hallmans, G;Hartikainen, AL;Hayward, C;Hernandez, D;Hicks, AA;Holm, H;Hung, YJ;Illig, T;Jones, MR;Kaleebu, P;Kastelein, JJP;Khaw, KT;Kim, E, .;et al.
國家衛生研究院 2013-11 Discovery and refinement of loci associated with lipid levels Consoutium, Global Lipids Genetics
國家衛生研究院 2014-08 Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors Cheng, MF;Hung, MS;Song, JS;Lin, SY;Liao, FY;Wu, MH;Hsiao, W;Hsieh, CL;Wu, JS;Chao, YS;Shih, C;Wu, SY;Ueng, SH
國家衛生研究院 2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins Chi, YH;Yeh, TK;Ke, YY;Lin, WH;Tsai, CH;Wang, WP;Chen, YT;Su, YC;Wang, PC;Chen, YF;Wu, ZW;Yeh, JY;Hung, MC;Wu, MH;Wang, JY;Chen, CP;Song, JS;Shih, C;Chen, CT;Chang, CP
朝陽科技大學 2003 Discovery Customer Requirements By Using Three Tiers Text Categorization 嚴國慶; 王淑卿; 林佩樺; 魏家惠
中國醫藥大學 2007-12-04 Discovery for New Drugs to Activate AMP-activate protein kinase by Computer Aided Drug Design (Jauo-Guei Yang); 陳語謙(Chen, Yu-Chian)
臺大學術典藏 2018-09-10T08:41:17Z Discovery in Drell-Yan Processes at the LHC Chiang, Cheng-Wei and Christensen, Neil D. and Ding, Gui-Jun and Han, Tao; CHENG-WEI CHIANG
國立成功大學 2015-07 Discovery in Tainan Train Station TSOI, Asta Waikwan
佛光大學 2004-06-01 Discovery learning,representation, and explanation within a computer-based simulation: Finding the right mix 曾世綺;Rieber, L. P.;Tzeng, S. C.;Kelly, T.
國家衛生研究院 2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist Hung, MS;Chang, CP;Li, TC;Yeh, TK;Song, JS;Lin, Y;Wu, CH;Kuo, PC;Amancha, PK;Wong, YC;Hsiao, WC;Chao, YS;Shia, KS
國家衛生研究院 2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice Chang, CP;Wu, CH;Song, JS;Chou, MC;Wong, YC;Lin, Y;Yeh, TK;Sadani, AA;Ou, MH;Chen, KH;Chen, PH;Kuo, PC;Tseng, CT;Chang, KH;Tseng, SL;Chao, YS;Hung, MS;Shia, KS
國家衛生研究院 2015-08 Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors Shiao, HY;Wang, WC;Hsu, YC;Ke, YY;Hsu, TA;Hsieh, HP
國家衛生研究院 2009-07-23 Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice Wu, CH;Hung, MS;Song, JS;Yeh, TK;Chou, MC;Chu, CM;Jan, JJ;Hsieh, MT;Tseng, SL;Chang, CP;Hsieh, WP;Lin, Y;Yeh, YN;Chung, WL;Kuo, CW;Lin, CY;Shy, HS;Chao, YS;Shia, KS
中國醫藥大學 2010-01 Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-a production 陳建樹(Chien-Shu Chen); (C.-M. Tan); (C.-H. Huang); (L.-C. Chang); (J.-P. Wang); (F.-C. Cheng); (J.-W. Chern)*
國立臺灣大學 2010 Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production Chen, Chien-Shu; Tan, Chen-Ming; Huang, Chiung-Hua; Chang, Ling-Chu; Wang, Jih-Pyang; Cheng, Fong-Chi; Chern, Ji-Wang
國家衛生研究院 2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院 2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Liou, JP; Wu, ZY; Kuo, CC; Chang, CY; Lu, PY; Chen, CM; Hsieh, HP; Chang, JY
臺北醫學大學 2008 Discovery of 4-Amino and 4-Hydroxy-1-Aroylindoles as Potent Tubulin Polymerization Inhibitors 劉景平; Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY
國立成功大學 2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Liou, Jing-Ping; Wu, Zi-Yi; Kuo, Ching-Chuan; Chang, Chi-Yen; Lu, Pei-Yi; Chen, Chi-Ming; Hsieh, Hsing-Pang; Chang, Jang-Yang
國立成功大學 2011-07-14 Discovery of 4-Anilinofuro[2,3-b]quinoline Derivatives as Selective and Orally Active Compounds against Non-Small-Cell Lung Cancers Chen, Yu-Wen; Chen, Yeh-Long; Tseng, Chih-Hua; Liang, Chih-Chung; Yang, Chia-Ning; Yao, Yun-Chin; Lu, Pei-Jung; Tzeng, Cherng-Chyi
國立成功大學 2022-04 Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes Chang;Yi-Han;Yen;Chia-Hung;Lai;Chih-Chung;Lai;Hsuan-Yu;Hung;Hsin-Yi
國家衛生研究院 2022-06-02 Discovery of a biomarker signature that reveals a molecular mechanism underlying diabetic kidney disease via organ cross talk Wu, IW;Tsai, TH;Lo, CJ;Chou, YJ;Yeh, CH;Cheng, ML;Lai, CC;Sytwu, HK;Tsai, TF
國家衛生研究院 2019-09-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2024-04-09 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus Chang, CP;Yeh, TK;Chen, CT;Wang, WP;Chen, YT;Tsai, CH;Chen, YF;Ke, YY;Wang, JY;Chen, CP;Hsieh, TC;Wu, MH;Huang, CL;Chen, YP;Zhuang, H;Chi, YH
國立交通大學 2018-08-21T05:53:19Z Discovery of a magnetic conductive interface in PbZr0.2Ti0.8O3 /SrTiO3 heterostructures Zhang, Yi; Xie, Lin; Kim, Jeongwoo; Stern, Alex; Wang, Hui; Zhang, Kui; Yan, Xingxu; Li, Linze; Liu, Henry; Zhao, Gejian; Chi, Hang; Gadre, Chaitanya; Lin, Qiyin; Zhou, Yichun; Uher, Ctirad; Chen, Tingyong; Chu, Ying-Hao; Xia, Jing; Wu, Ruqian; Pan, Xiaoqing
國家衛生研究院 2021-10-09 Discovery of a metabolic signature predisposing high risk patients with mild cognitive impairment to converting to Alzheimer’s disease Huang, YL;Lin, CH;Tsai, TH;Huang, CH;Li, JL;Chen, LK;Li, CH;Tsai, TF;Wang, PN
臺大學術典藏 2020-02-14T03:15:34Z Discovery of a Metalloenzyme-like Cooperative Catalytic System of Metal Nanoclusters and Catechol Derivatives for the Aerobic Oxidation of Amines Shu¯ Kobayashi; Hiroyuki Miyamura; Woo-Jin Yoo; Hao Yuan
淡江大學 2020-06-24 Discovery of a more potent anti-cancer agent than C4-benzazole 1,8-naphthalimide derivatives against murine melanoma Tung, Chi-Hua;Lu, Yen-Ta;Kao, Wei-Ting;Liu, Jen-Wei;Lai, Yi-Hsuan;Jiang, Shinn-Jong;Chen, Hao-Ping;Shih, Tzenge-Lien

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